Anti-Human CD276/B7-H3 Reference Antibody (Tambotatug, RUO) (HV612106)

Name: Anti-Human CD276/B7-H3 Reference Antibody (Tambotatug, RUO)
Brand: abinScience
SKU: HV612106
Price: 370 USD
Availability: InStock

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100ug
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Número de catálogo	HV612106
Descripción	tambotatug (HV612106) is a research-grade recombinant antibody targeting CD276. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especies	Human
Aplicaciones	ELISA, FCM, Functional assay
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
Objetivo	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Número de acceso	Q5ZPR3
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CAS: 2925042-44-8
Fondo	CD276 antigen is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses.
Nota	For research use only.