Anti-Human CD276/B7-H3 Reference Antibody (Tambotatug, RUO) (HV612106)

Name: Anti-Human CD276/B7-H3 Reference Antibody (Tambotatug, RUO)
Brand: abinScience
SKU: HV612106
Price: 370 USD
Availability: InStock

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Numéro de catalogue	HV612106
Description	tambotatug (HV612106) is a research-grade recombinant antibody targeting CD276. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactivité des espèces	Human
Applications	ELISA, FCM, Functional assay
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, kappa
Cible	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Numéro d'accès	Q5ZPR3
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CAS: 2925042-44-8
Contexte	CD276 antigen is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses.
Note	For research use only.