Anti-Human CD40/TNFRSF5 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Tecaginlimab, RUO) (HB782126)

Name: Anti-Human CD40/TNFRSF5 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Tecaginlimab, RUO)
Brand: abinScience
SKU: HB782126
Price: 220 USD
Availability: InStock

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100ug
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Даташит
SDS

Обзор

Каталожный номер	HB782126
Описание	Tecaginlimab (HB782126) is a research-grade recombinant antibody targeting CD40. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Проверенные приложения	FCM
Цель	B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P25942 & Q07011
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Bispecific, BNT-312, DuoBody-CD40x-4-1BB, GEN1042, GEN-1042, GEN10422253891-70-0
Фон	Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Изображения

Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Tecaginlimab.
Flow CytoMetry

Flow-cytometry using APC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD40 monoclonal antibody (Catalog: HB782126, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD40 monoclonal antibody (Catalog: HB782126, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Ссылки

Даташит

Anti-Human CD40/TNFRSF5 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Tecaginlimab, RUO).pdf

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Formula

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