Anti-Human EGFR & HGFR/c-MET Bispecific Reference Antibody (Tilatamig, RUO) (HY196206)

Name: Anti-Human EGFR & HGFR/c-MET Bispecific Reference Antibody (Tilatamig, RUO)
Brand: abinScience
SKU: HY196206
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HY196206
Description	Tilatamig (HY196206) is a research-grade recombinant antibody targeting Tyrosine-protein kinase Met. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa/G1-lambda
Système d'expression	Mammalian cells
Applications testées	FCM
Cible	Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET, HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P08581 & P00533
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Bispecific, 2868265-50-1
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE

SDS-PAGE for Research Grade Tilatamig.
Bioactivity

Detects recombinant human EGFR/ERBB1/HER1 (Catalog No: HF004011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human MET antibody. HT-29 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human MET monoclonal antibody (Catalog HY196206, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using anti-human EGFR antibody. Transfected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human EGFR monoclonal antibody (Catalog HY196206, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Reférences

Fiche technique

Anti-Human EGFR & HGFR/c-MET Bispecific Reference Antibody (Tilatamig, RUO).pdf

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