

| Número de catálogo | SW328026 | ||||
|---|---|---|---|---|---|
| Descripción |
Research Grade Tirzepatide (SW328026) is a rabbit polyclonal antibody detecting GLP-1 receptor in ELISA, Functional assay, Research in vivo. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA, Functional assay, Research in vivo | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | Biosynthetic peptide. | ||||
| Sistema de expresión | Mammalian cells | ||||
| Naturaleza | Recombinant | ||||
| Objetivo | GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R, Gastric inhibitory polypeptide receptor, GIPR, GIP-R, Glucose-dependent insulinotropic polypeptide receptor | ||||
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Purified by HPLC. | ||||
| Número de acceso | P43220 & P48546 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Nombres alternativos | 2023788-19-2 | ||||
| Fondo | Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. 1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722 2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095 3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125 4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449 5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895 6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285 7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712 | ||||
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
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