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Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO) (HV213046)

Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)
Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)
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Aperçu
Numéro de catalogueHV213046
Description
Ucenprubart (HV213046) is a research-grade recombinant antibody targeting CD200. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4-kappa
Système d'expression Mammalian cells
Cible MOX2R, Cell surface glycoprotein OX2 receptor 1, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200R, CD200 cell surface glycoprotein receptor, CRTR2, CD200R1
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q8TD46
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs2414559-57-0
Contexte

Cell surface glycoprotein CD200 receptor 1 (CD200R1/OX2R) is a ~39 kDa protein. Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Images
  • Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Ucenprubart.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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