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Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO) (HB209026)

Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
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  • 1mg
  • 5mg
  • 10mg
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  • 概要

  • イメージ

  • 参考文献

  • データシート

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概要
カタログ番号HB209026
説明
Uliledlimab (HB209026) is a research-grade recombinant antibody targeting CD73. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG1-Kappa
ターゲット 5'-NT, 5'-deoxynucleotidase, 5'-nucleotidase, CD73, EC:3.1.3.35, EC:3.1.3.5, EC:3.1.3.89, EC:3.1.3.91, EC:3.1.3.99, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, NT5, NT5E, NTE, Thymidylate 5'-phosphatase
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P21589
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名TJ-004309, TJC-4309, TJD-5, 2378407-27-1
背景

5'-nucleotidase (CD73/NT5E) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN.

1. Garavaglia, S. et al. (2012) The Biochemical journal 441, 131-41. PMID: 21933152
2. Heuts, DP. et al. (2012) Chembiochem : a European journal of chemical biology 13, 2384-91. PMID: 22997138
3. Knapp, K. et al. (2012) Structure (London, England : 1993) 20, 2161-73. PMID: 23142347
4. Fausther, M. et al. (2014) PloS one 9, e98568. PMID: 24887587
5. Scaletti, E. et al. (2021) Purinergic signalling 17, 693-704. PMID: 34403084
注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)
イメージ
  • Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Uliledlimab.

  • Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)

    Bioactivity

    Detects CD73/NT5E in indirect ELISAs.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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