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Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO) (HB209026)

Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHB209026
Описание
Uliledlimab (HB209026) is a research-grade recombinant antibody targeting CD73. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-Kappa
Цель 5'-NT, 5'-deoxynucleotidase, 5'-nucleotidase, CD73, EC:3.1.3.35, EC:3.1.3.5, EC:3.1.3.89, EC:3.1.3.91, EC:3.1.3.99, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, NT5, NT5E, NTE, Thymidylate 5'-phosphatase
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P21589
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияTJ-004309, TJC-4309, TJD-5, 2378407-27-1
Фон

5'-nucleotidase (CD73/NT5E) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN.

1. Garavaglia, S. et al. (2012) The Biochemical journal 441, 131-41. PMID: 21933152
2. Heuts, DP. et al. (2012) Chembiochem : a European journal of chemical biology 13, 2384-91. PMID: 22997138
3. Knapp, K. et al. (2012) Structure (London, England : 1993) 20, 2161-73. PMID: 23142347
4. Fausther, M. et al. (2014) PloS one 9, e98568. PMID: 24887587
5. Scaletti, E. et al. (2021) Purinergic signalling 17, 693-704. PMID: 34403084
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)
Изображения
  • Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Uliledlimab.

  • Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Uliledlimab, RUO)

    Bioactivity

    Detects CD73/NT5E in indirect ELISAs.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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Список дистрибьюторов