Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO) (HV684016)

Name: Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO)
Brand: abinScience
SKU: HV684016
Price: 400 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV684016
Description	Vepsitamab (HV684016) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	(scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
Système d'expression	Mammalian cells
Cible	MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q685J3 & P07766
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Bispecific, AMG199, AMG-199, AMG1992413453-53-7
Contexte	Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) Human IgG1 (E356D/M358L), kappa Recombinant Isotype Control Antibody (HyHEL-10) (HV080013) Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

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Bioactivity

Detects Recombinant Human MUC17 Protein, N-His (Cat No.: HV684012) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-human MUC17 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human MUC17 (Catalog No: HV684012)
Lane 2: negative control
SDS-PAGE

SDS-PAGE for Research Grade Vepsitamab

Reférences

Fiche technique

Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO).pdf

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