Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO) (HV684016)

Name: Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO)
Brand: abinScience
SKU: HV684016
Price: 400 USD
Availability: InStock

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概要

カタログ番号	HV684016
説明	Vepsitamab (HV684016) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	(scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
発現システム	Mammalian cells
ターゲット	MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q685J3 & P07766
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	Bispecific, AMG199, AMG-199, AMG1992413453-53-7
背景	Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) Human IgG1 (E356D/M358L), kappa Recombinant Isotype Control Antibody (HyHEL-10) (HV080013) Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

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Bioactivity

Detects Recombinant Human MUC17 Protein, N-His (Cat No.: HV684012) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-human MUC17 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human MUC17 (Catalog No: HV684012)
Lane 2: negative control
SDS-PAGE

SDS-PAGE for Research Grade Vepsitamab

参考文献

データシート

Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO).pdf

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Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO) (HV684016)

概要

イメージ

参考文献

データシート

SDS

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