Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO) (HV684016)

Name: Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO)
Brand: abinScience
SKU: HV684016
Price: 400 USD
Availability: InStock

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100ug
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Обзор

Каталожный номер	HV684016
Описание	Vepsitamab (HV684016) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	(scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
Система экспрессии	Mammalian cells
Цель	MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q685J3 & P07766
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Bispecific, AMG199, AMG-199, AMG1992413453-53-7
Фон	Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) Human IgG1 (E356D/M358L), kappa Recombinant Isotype Control Antibody (HyHEL-10) (HV080013) Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Изображения

Bioactivity

Detects Recombinant Human MUC17 Protein, N-His (Cat No.: HV684012) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-human MUC17 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human MUC17 (Catalog No: HV684012)
Lane 2: negative control
SDS-PAGE

SDS-PAGE for Research Grade Vepsitamab

Ссылки

Даташит

Anti-Human MUC17/MUC3 & CD3 epsilon Bispecific Reference Antibody (Vepsitamab, RUO).pdf

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