Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

Name: Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)
Brand: abinScience
SKU: HB665016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB665016
Description	Vofatamab (HB665016) is a research-grade recombinant antibody targeting CD333. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Applications testées	WB
Cible	Fibroblast growth factor receptor 3, FGFR-3, FGFR3, JTK4, CD333
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P22607
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	MFGR1877S, MFGR-1877S, MFGR1877S, 1312305-12-6
Contexte	Fibroblast growth factor receptor 3 (CD333/FGFR3) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Vofatamab.
Bioactivity

Detects CD333/FGFR3 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Vofatamab.
Western blot

Western blot analysis was performed using anti-CD333/FGFR3 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD333/FGFR3 (Catalog No: HB665011)