Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

Name: Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)
Brand: abinScience
SKU: HB665016
Price: 176 USD
Availability: InStock

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100ug
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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	HB665016
Описание	Vofatamab (HB665016) is a research-grade recombinant antibody targeting CD333. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Проверенные приложения	WB
Цель	Fibroblast growth factor receptor 3, FGFR-3, FGFR3, JTK4, CD333
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P22607
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	MFGR1877S, MFGR-1877S, MFGR1877S, 1312305-12-6
Фон	Fibroblast growth factor receptor 3 (CD333/FGFR3) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

SEC-HPLC

SEC-HPLC detection for Research Grade Vofatamab.
Bioactivity

Detects CD333/FGFR3 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Vofatamab.
Western blot

Western blot analysis was performed using anti-CD333/FGFR3 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD333/FGFR3 (Catalog No: HB665011)