Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO) (HX959196)

Name: Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO)
Brand: abinScience
SKU: HX959196
Price: 320 USD
Availability: InStock

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100ug
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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX959196

Description

Vonsetamig (HX959196) is a research-grade recombinant antibody targeting CD269. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG4-kappa

Applications testées

WB, FCM

Cible

B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q02223 & P07766

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

2408319-33-3

Contexte

Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

Images

SDS-PAGE

SDS-PAGE for Research Grade Vonsetamig.
Flow cytometry

Flow-cytometry using anti-human CD3E antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD3E monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using anti-human CD269 antibody. Transfected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD269 monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Bioactivity

Detects recombinant CD269 (Catalog No: HX959012) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD3E (Catalog No: HY057021)
Lane 2: Negative control