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Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO) (HC669076)

Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
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Aperçu
Numéro de catalogueHC669076
Description
Voxalatamab (HC669076) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIg(G4-kappa_G4-lambda)
Système d'expression Mammalian cells
Applications testées FCM
Cible NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q04609 & P07766
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsBispecific, JNJ-63898081, JNJ-80812411871-58-2
ContexteVoxalatamab (JNJ-63898081) is a bispecific IgG4 antibody that binds PSMA and CD3 and has anti-cancer activity for use in prostate cancer research.
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
Images
  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using APC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using FITC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using PE anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using anti-human FOLH1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human FOLH1 monoclonal antibody (Catalog: HC669076) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
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Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
Recommandation

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