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Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO) (HC669076)

Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
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  • 概要

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概要
カタログ番号HC669076
説明
Voxalatamab (HC669076) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIg(G4-kappa_G4-lambda)
発現システム Mammalian cells
テスト済みアプリケーション FCM
ターゲット NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q04609 & P07766
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Bispecific, JNJ-63898081, JNJ-80812411871-58-2
背景Voxalatamab (JNJ-63898081) is a bispecific IgG4 antibody that binds PSMA and CD3 and has anti-cancer activity for use in prostate cancer research.
注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
イメージ
  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using APC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using FITC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using PE anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using anti-human FOLH1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human FOLH1 monoclonal antibody (Catalog: HC669076) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
Formula
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