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Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO) (HC669076)

Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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Обзор
Каталожный номерHC669076
Описание
Voxalatamab (HC669076) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIg(G4-kappa_G4-lambda)
Система экспрессии Mammalian cells
Проверенные приложения FCM
Цель NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q04609 & P07766
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияBispecific, JNJ-63898081, JNJ-80812411871-58-2
ФонVoxalatamab (JNJ-63898081) is a bispecific IgG4 antibody that binds PSMA and CD3 and has anti-cancer activity for use in prostate cancer research.
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
Изображения
  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using APC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using FITC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using PE anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human FOLH1 monoclonal antibody (Catalog: HC669076, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA & CD3 epsilon Bispecific Reference Antibody (Voxalatamab, RUO)

    Flow CytoMetry

    Flow-cytometry using anti-human FOLH1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human FOLH1 monoclonal antibody (Catalog: HC669076) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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