Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

Name: Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO)
Brand: abinScience
SKU: HV631046
Price: 176 USD
Availability: InStock

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Número de catálogo	HV631046
Descripción	zamristobart (HV631046) is a research-grade recombinant antibody targeting CD85. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especies	Human
Aplicaciones	ELISA, FCM, Functional assay
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4, kappa
Sistema de expresión	Mammalian cells
Naturaleza	Recombinant
Objetivo	CD85j/LILRB1/ILT2
Nivel de endotoxinas	< 10 EU/mg as determined by LAL method.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q8NHL6
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CAS: 3036192-53-4
Fondo	Leukocyte immunoglobulin-like receptor subfamily B member 1 is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
Nota	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade zamristobart

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Datasheet

Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

Vista general

Imágenes

Referencias

Datasheet

SDS