Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

Name: Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO)
Brand: abinScience
SKU: HV631046
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HV631046
Description	zamristobart (HV631046) is a research-grade recombinant antibody targeting CD85. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactivité des espèces	Human
Applications	ELISA, FCM, Functional assay
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG4, kappa
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	CD85j/LILRB1/ILT2
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q8NHL6
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CAS: 3036192-53-4
Contexte	Leukocyte immunoglobulin-like receptor subfamily B member 1 is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
Note	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO).pdf

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Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

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