Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

Name: Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO)
Brand: abinScience
SKU: HV631046
Price: 176 USD
Availability: InStock

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概要

カタログ番号	HV631046
説明	zamristobart (HV631046) is a research-grade recombinant antibody targeting CD85. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
種反応性	Human
アプリケーション	ELISA, FCM, Functional assay
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG4, kappa
発現システム	Mammalian cells
性質	Recombinant
ターゲット	CD85j/LILRB1/ILT2
エンドトキシンレベル	< 10 EU/mg as determined by LAL method.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q8NHL6
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CAS: 3036192-53-4
背景	Leukocyte immunoglobulin-like receptor subfamily B member 1 is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
注意事項	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade zamristobart

参考文献

データシート

Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO).pdf

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Anti-Human LILRB1/CD85j/ILT2 Reference Antibody (Zamristobart, RUO) (HV631046)

概要

イメージ

参考文献

データシート

SDS