Anti-Human ErbB2/Her2 & ErbB3/Her3 Bispecific Reference Antibody (Zenocutuzumab, RUO) (HY286096)

Name: Anti-Human ErbB2/Her2 & ErbB3/Her3 Bispecific Reference Antibody (Zenocutuzumab, RUO)
Brand: abinScience
SKU: HY286096
Price: 176 USD
Availability: InStock

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SDS

Vista general

Número de catálogo	HY286096
Descripción	Zenocutuzumab (HY286096) is a research-grade recombinant antibody targeting CD340. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
Aplicaciones probadas	WB, FCM
Objetivo	CD340, EC:2.7.10.1, ERBB2, HER2, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NGL, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, EC:2.7.10.1, ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P04626 & P21860
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Bispecific, MCLA-128, PB4188, R040517, 1969309-56-5
Fondo	Zenocutuzumab (MCLA-128) is a bispecific humanized IgG1 antibody containing two different Fab arms, targeting extracellular domains of HER2 and HER3.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407) Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Bioactivity

Detects CD340/ERBB2/HER2/NEU in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Zenocutuzumab
Flow CytoMetry

Flow-cytometry using anti-human ERBB3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ERBB3 monoclonal antibody (Catalog: HY286096) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD340/ERBB2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD340/ERBB2 (Catalog No: HY286011)

Referencias

Datasheet

Anti-Human ErbB2/Her2 & ErbB3/Her3 Bispecific Reference Antibody (Zenocutuzumab, RUO).pdf

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Formula

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