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| 카탈로그 번호 | MP717014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 이소타입 | IgG | ||||||||
| 클론성 | Polyclonal | ||||||||
| 면역원 | E. coli - derived recombinant Mouse ERAP1 (Glu45-Asp226). | ||||||||
| 타겟 | Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9EQH2 | ||||||||
| RRID | Anti-Mouse ERAP1 Polyclonal Antibody (abinScience Cat# MP717014, RRID:AB_3723595) |
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| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a ~106 kDa protein. Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-Mouse ERAP1 polyclonal antibody at 1ug/mL on recombinant Mouse ERAP1 (Catalog No. MP717012).
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