Anti-Cannabinoid receptor 1 Antibody (L112/22) (HB822043)

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가격(USD): $

사양:

50ug
100ug
1mg

수량:

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개요
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개요

카탈로그 번호

HB822043

설명

Anti-Cannabinoid receptor 1 Antibody (L112/22) [L112/22] (HB822043) is a mouse monoclonal antibody detecting Cannabinoid receptor 1 in IHC, WB.

응용 분야

IHC, WB

숙주 종

Mouse

이소타입

IgG2a, kappa

클론 ID

L112/22

클론성

Monoclonal

타겟

CNR1, CB1, CANN6, CB-R, CNR, Cannabinoid receptor 1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P21554,P47746,P20272

RRID

Anti-Cannabinoid receptor 1 Antibody (L112/22) (abinScience Cat# HB822043, RRID:AB_3728154)

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Cannabinoid receptor 1 (CNR1/CB1) is a ~52 kDa protein. G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrahydrocannabinol (THC). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while decreases respiration at high doses.

1. Ryberg, E. et al. (2005) FEBS letters 579, 259-64. PMID: 15620723

2. Hua, T. et al. (2016) Cell 167, 750-762.e14. PMID: 27768894

3. Shao, Z. et al. (2016) Nature 540, 602-606. PMID: 27851727

4. Yang, X. et al. (2022) Nature chemical biology 18, 831-840. PMID: 35637350

5. Gérard, CM. et al. (1991) The Biochemical journal 279 ( Pt 1), 129-34. PMID: 1718258

6. Oddi, S. et al. (2012) British journal of pharmacology 165, 2635-51. PMID: 21895628

7. Niehaus, JL. et al. (2007) Molecular pharmacology 72, 1557-66. PMID: 17895407

8. Jourdan, T. et al. (2013) Nature medicine 19, 1132-40. PMID: 23955712

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Cannabinoid receptor 1 Antibody (L112/22)

참고 문헌

데이터시트

Anti-Cannabinoid receptor 1 Antibody (L112/22).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Cannabinoid receptor 1 Antibody (L112/22) (HB822043)

개요

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