Anti-Optineurin Antibody (6A7.1) (HP451013)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

20ug
50ug
100ug
1mg

수량:

문의하기

개요
이미지
참고 문헌
데이터시트

개요

카탈로그 번호

HP451013

설명

Anti-Optineurin Antibody (6A7.1) [6A7.1] (HP451013) is a mouse monoclonal antibody detecting Optineurin in IHC, WB. Suitable for Human.

종 반응성

Human

응용 분야

IHC, WB

숙주 종

Mouse

이소타입

IgG2a

클론 ID

6A7.1

클론성

Monoclonal

타겟

NRP, TFIIIA-IntP, Huntingtin-interacting protein 7, HIP-7, Huntingtin yeast partner L, Transcription factor IIIA-interacting protein, NEMO-related protein, E3-14.7K-interacting protein, GLC1E, HIP7, HYPL, FIP-2, Huntingtin-interacting protein L, Optic neuropathy-inducing protein, OPTN, Optineurin, FIP2

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

Q96CV9

RRID

Anti-Optineurin Antibody (6A7.1) (abinScience Cat# HP451013, RRID:AB_3728971)

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Optineurin (OPTN) is a ~65 kDa protein. Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Plays a role in the activation of innate immune response during viral infection. Mechanistically, recruits TBK1 at the Golgi apparatus, promoting its trans-phosphorylation after RLR or TLR3 stimulation. In turn, activated TBK1 phosphorylates its downstream partner IRF3 to produce IFN-beta/IFNB1.

1. Fifita, JA. et al. (2017) Amyotrophic lateral sclerosis & frontotemporal degeneration 18, 126-133. PMID: 27534431

2. Pourcelot, M. et al. (2016) BMC biology 14, 69. PMID: 27538435

3. Vaibhava, V. et al. (2012) Journal of cell science 125, 5026-39. PMID: 22854040

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Optineurin Antibody (6A7.1)

참고 문헌

데이터시트

Anti-Optineurin Antibody (6A7.1).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Optineurin Antibody (6A7.1) (HP451013)

개요

이미지

참고 문헌

데이터시트

빠른 접근

문의하기