

| 카탈로그 번호 | VK560023 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270) [SAA2270] (VK560023) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA. Suitable for Influenza A virus.
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| 종 반응성 | Influenza A virus | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Alpaca | ||||
| 이소타입 | VHH-His | ||||
| 클론 ID | SAA2270 | ||||
| 클론성 | Monoclonal | ||||
| 타겟 | Polymerase acidic protein, RNA-directed RNA polymerase subunit P2, PA | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >90% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P03427 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Polymerase basic protein 2 (RNA polymerase complex) is a ~85 kDa protein. Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS. | ||||
| 참고사항 | For research use only. |

SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270)


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