

| Numéro de catalogue | MC589013 |
|---|---|
| Reactivité des espèces | Mouse |
| Applications | IP, WP, Block, FCM, IHC |
| Espèce hôte | Rat |
| Clonalité | Monoclonal |
| Isotype | IgG2a, kappa |
| ID de clone | MECA-367 |
| Cible | MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1 |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | Q61826 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
| Note | For research use only |
| Isotype Control | Rat IgG2a Recombinant Isotype Control Antibody (SPE-7) (RF533107) |

SDS-PAGE for Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-367)




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