

| Каталожный номер | MC589023 |
|---|---|
| Описание |
Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-89) (MC589023) is a rat monoclonal antibody detecting MAdCAM-1 in IP, WP, Block, FCM, IHC. Suitable for Mouse.
Highlights
|
| Реактивность видов | Mouse |
| Применения | IP, WP, Block, FCM, IHC |
| Хозяинский вид | Rat |
| Клоональность | Monoclonal |
| Изотип | IgG2a, kappa |
| ID клона | MECA-89 |
| Цель | MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1 |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q61826 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
| Примечание | For research use only. |




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