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| カタログ番号 | VK059023 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-pan-Ebola virus Nucleoprotein Antibody (SAA2995) (VK059023) is a monoclonal antibody detecting Nucleoprotein in ELISA. Suitable for Bundibugyo virus (BDBV), Tai Forest ebolavirus (TAFV) (Cote d'Ivoire Ebola virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus).
Highlights
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| 種反応性 | Bundibugyo virus (BDBV), Tai Forest ebolavirus (TAFV) (Cote d'Ivoire Ebola virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| アプリケーション | ELISA | ||||
| クローン性 | Monoclonal | ||||
| クローンID | SAA2995 | ||||
| ターゲット | Nucleoprotein | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Nucleoprotein (NP) is a ~56 kDa protein. Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. | ||||
| 注意事項 | For research use only. |
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