Anti-Human CHMP4B Polyclonal Antibody (HB565024)

Name: Anti-Human CHMP4B Polyclonal Antibody
Brand: abinScience
SKU: HB565024
Price: 168 USD
Availability: InStock

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Каталожный номер

HB565024

Описание

Anti-Human CHMP4B Polyclonal Antibody (HB565024) is a rabbit polyclonal antibody detecting CHMP4B in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CHMP4B (Asp121-Met224).

Цель

C20orf178, CHMP4B, CHMP4b, Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, SHAX1, SNF7 homolog associated with Alix 1, SNF7-2, Vacuolar protein sorting-associated protein 32-2, Vps32-2, hSnf7-2, hVps32-2

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q9H444

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Фон

Charged multivesicular body protein 4b (CHMP4B) is a ~24 kDa protein. Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.

1. Katoh, K. et al. (2003) The Journal of biological chemistry 278, 39104-13. PMID: 12860994

2. Hanson, PI. et al. (2008) The Journal of cell biology 180, 389-402. PMID: 18209100

3. Guizetti, J. et al. (2011) Science (New York, N.Y.) 331, 1616-20. PMID: 21310966

4. Vietri, M. et al. (2015) Nature 522, 231-5. PMID: 26040712

5. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413

6. Baeumers, M. et al. (2020) BMC biology 18, 200. PMID: 33349255

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human CHMP4B Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human CHMP4B Polyclonal Antibody (HB565024)

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