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Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141) (MY474013)

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Aperçu
Numéro de catalogueMY474013
Description
Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141) (MY474013) is a mouse monoclonal antibody detecting CD11b/ITGAM in ELISA. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactivité des espècesMouse
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneASD-141
Cible CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P05555
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295
2. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116
3. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980
4. Jerke, U. et al. (2011) The Journal of biological chemistry 286, 7070-81. PMID: 21193407
5. Diamond, MS. et al. (1990) The Journal of cell biology 111, 3129-39. PMID: 1980124
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141)

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