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Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7) (MY474207)

Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7)
Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7)
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Overview
Catalog No.MY474207
Species reactivityHuman, Mouse
ApplicationsELISA, FCM
IsotypeDARPin
Clone IDF7
Clonality Monoclonal
Target Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Purified by Nickel column.
Accession P05555
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038
Note For research use only.
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  • Anti-Mouse CD11b/ITGAM Recombinant Antibody (F7)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD11b/ITGAM Antibody (F7)

References
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