Therapeutic Targets

abinScience provides drug-development-grade reagents for over 150 therapeutic targets — including PD-1/PD-L1, CD3, EGFR, HER2, VEGF, CTLA-4, BCMA, TROP2, CD47, and CCR8. Our portfolio covers recombinant proteins, validated antibodies, ELISA kits, biosimilar reference standards, and stable cell lines, giving you a single source for target validation, bioassay development, PK/ADA assays, and functional studies. Select a target below to browse all available products.

Why Researchers Choose abinScience for Target Reagents

Complete Target Coverage Recombinant proteins (His, Fc, Avi, biotinylated), monoclonal and polyclonal antibodies, ELISA kits, biosimilar reference standards, and stable cell lines — all from one supplier.

Bioassay-Validated Proteins Key recombinant proteins are validated by SPR/BLI binding kinetics, cell-based functional assays, and SDS-PAGE/SEC-HPLC purity analysis. Lot-specific CoA included.

PK/ADA Assay-Ready Pairs Validated capture/detection antibody pairs and calibrator proteins for pharmacokinetic and anti-drug antibody ELISA development. Matched pair datasheets available.

Biosimilar Reference Standards Research-grade biosimilars of approved therapeutic antibodies (Pembrolizumab, Nivolumab, Trastuzumab, Bevacizumab, Atezolizumab, etc.) for analytical comparability studies.

How to Select the Right Target Reagent

Define your application. Biomarker detection (WB, IHC, FC) → antibodies. Binding kinetics or functional assay → recombinant proteins. Quantification → ELISA kits. Comparability study → biosimilar reference standards.

Choose the right protein format. His-tagged for Ni-NTA purification and ELISA coating. Fc-chimera for extended half-life and Protein A capture. Avi-tagged/biotinylated for oriented immobilization in SPR/BLI.

Verify species and validation data. Check that the product is validated for your target species and application. Download the lot-specific CoA from the product page for purity, activity, and endotoxin data.

Need custom work? If your target isn't in our catalog or you need a specific format, our parent CRO AtaGenix can develop custom antibodies and proteins from sequence to purified product.

Frequently Asked Questions

What protein formats are available for therapeutic targets?

Most targets are available in His-tagged, Fc-chimera, Avi-tagged, and biotinylated formats. Specific formats vary by target — check the individual target page for available options. Custom formats can be produced through our CRO service.

Are your proteins suitable for SPR/BLI binding assays?

Yes. Avi-tagged and biotinylated proteins are designed for oriented immobilization on streptavidin-coated sensor chips (Biacore) or biosensors (Octet). His-tagged proteins can also be immobilized via Ni-NTA surfaces. Kinetics data is available on select product pages.

Do you offer matched antibody pairs for PK/ADA ELISA development?

Yes. We provide validated capture/detection antibody pairs and calibrator proteins for several major therapeutic targets. These pairs are designed for sandwich ELISA-based pharmacokinetic (PK) and anti-drug antibody (ADA) assay development. Contact us for pair availability for your specific target.

What is the difference between a research biosimilar and a reference standard?

Our research biosimilars are RUO (Research Use Only) recombinant antibodies with sequences matching approved therapeutics. They are produced in mammalian expression systems (CHO/HEK293) and are suitable for analytical comparability studies, bioassay development, and positive controls — but are not GMP-grade and should not be used for clinical or diagnostic purposes.

Can I order bulk quantities for GLP studies?

Yes. We offer bulk packaging with enhanced documentation for regulated preclinical studies. Contact us for custom quotes, bulk pricing, and lead times.