Characterize adeno-associated virus (AAV) capsids and screen for pre-existing anti-AAV immunity with serotype-specific antibodies and recombinant capsid proteins. Our portfolio covers AAV2, AAV3, AAV5, AAV6, AAV8, and AAV9 — the serotypes most widely used in gene therapy vectors — with recombinant antibodies validated for neutralization, ELISA, dot blot, and intact-particle detection, polyclonal antibodies for WB and IHC, and His-tagged VP1/VP2/VP3 recombinant proteins for immunoassay development. RUO
All products manufactured by AtaGenix Laboratories under ISO 9001 & ISO 13485 quality systems.
1. Wang D, Tai PWL, Gao G. Adeno-associated virus vector as a platform for gene therapy delivery. Nat Rev Drug Discov. 2019;18(5):358-378. DOI
2. Boutin S, Monteilhet V, Veron P, et al. Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population. Hum Gene Ther. 2010;21(6):704-712. DOI
Adeno-associated virus 2 (AAV2)
ELISA, WB
Human
IgG1, kappa
SAA0362
Adeno-associated virus 2 (AAV2)
Dot blot, ELISA, ICC/IF, IP, Neutralization
Mouse
IgG3
A20
Adeno-associated virus 2 (AAV2)
Dot blot, ELISA, ICC/IF, IP, Neutralization
Mouse
IgG1
A20R
Adeno-associated virus 2 (AAV2)
ELISA, IF
Mouse
IgG2a, kappa
SAA0358
E. coli
AAN03857.1
Asp220-Leu738
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Adeno-associated virus 8 (AAV8)
E. coli
P03135
Gly226-Gln461
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Adeno-associated virus 2 (AAV2)
Adeno-associated virus 2 (AAV2)
ELISA, IHC, WB
Rabbit
IgG