Anti-PEG Antibodies | PEGylated Drug Detection

Detect polyethylene glycol (PEG) and PEGylated molecules with anti-PEG antibodies targeting PEG backbone, methoxy-PEG (mPEG), and hydroxyl-PEG (OH-PEG). PEGylation improves PK of therapeutic proteins, peptides, oligonucleotides, and mRNA-LNP vaccines. For PK/biodistribution, anti-PEG immunogenicity screening, and LNP characterization. All products are designated Research Use Only (RUO) — not intended for diagnostic or therapeutic procedures. RUO

Why Researchers Choose abinScience

Backbone & Terminal Specificity Anti-PEG backbone detects all PEGylated molecules; anti-mPEG and anti-OH-PEG distinguish terminal chemistry for PEGylation site characterization.

PEGylated Drug PK Capture/detection in sandwich ELISA for PEGylated drug concentrations. Compatible with PEG-interferon, PEG-asparaginase, PEG-liposomes, and PEG-LNPs.

Anti-PEG Immunogenicity Pre-existing anti-PEG IgG/IgM cause accelerated blood clearance (ABC) and hypersensitivity. Enable bridging ELISA for anti-PEG antibody detection in clinical samples.

mRNA-LNP Vaccine Research PEG-lipids (ALC-0159, DMG-PEG2000) in mRNA-LNP. Support LNP characterization, PEG surface density quantification, and anti-PEG immune monitoring.

Matched ELISA Pairs Validated capture + detection pairs. Unconjugated, HRP, biotinylated. Both IgG and IgM isotype anti-PEG clones available.