XtenNano® Nanobodies | VHH Single-Domain Antibodies

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Discover 900+ XtenNano® recombinant nanobodies — single-domain antibodies (VHH) derived from camelid heavy-chain-only immunoglobulins. At just ~15 kDa, nanobodies offer superior tissue penetration, exceptional thermal/chemical stability, and access to hidden epitopes unreachable by conventional IgG antibodies. Ideal for super-resolution microscopy, intracellular targeting, and affinity purification. All products are designated Research Use Only (RUO) — not intended for diagnostic or therapeutic procedures. RUO

Why Researchers Choose abinScience

Ultra-Small (~15 kDa) One-tenth the size of conventional IgG — enabling deeper tissue penetration, faster clearance, and access to sterically restricted epitopes in crowded molecular environments.

Super-Resolution Imaging Smaller labeling radius improves localization precision in STORM, PALM, and STED microscopy. Pre-conjugated to fluorophores for direct use in advanced imaging workflows.

High Stability Resistant to extreme pH, temperature, and chemical denaturants. Suitable for harsh fixation protocols, intracellular staining, and applications where conventional antibodies lose activity.

Recombinant & Sequence-Defined Every XtenNano® nanobody is recombinantly produced with a defined sequence — ensuring absolute lot-to-lot reproducibility and enabling genetic fusion to reporters or tags.

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Product types

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Research Biosimilar (20)

Antibodies (1000)
Expression system

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Mammalian cells (21)
Target

0 selected

DLL4 (1)

CD154/CD40L (1)

NOTCH3 (1)

B2M/β2M (2)

AMY2 (1)

Shiga toxin 2 subunit B/stx2eB (2)

Fusion glycoprotein F0 (1)

GCN4/AAS3 (1)

CD136/MST1R (1)

BC2 tag (1)

Glycoprotein G1 (1)

GPC3/Glypican 3 (1)

RAGE-1/MOK (2)

E6/Protein E6 (4)

PTH1R (2)

HHRF3/US28 (5)

Genome polyprotein (1)

CRP (2)

GP2 (1)

AKT3 (1)

GP6/GPVI (1)

CTGF/CCN2 (1)

NOTCH2 (1)

TTYH2 (1)

TRIM28 (1)

LYZ/LysozymeC (1)

nef/F-protein/Negative factor (1)

CD326/EPCAM (1)

CD1d (1)

CD8A (2)

WFDC2/HE4 (1)

CD49e/ITGA5 (1)

IL23R (3)

ADAM12 (2)

MAGEB1 (3)

F11/Coagulation factor XI (1)

LYZ/Lysozyme C (7)

G9 (2)

CD32b/FCGR2B (1)

NPTX2 (2)

SLC5A1 (1)

CDH17/Cadherin-17 (2)

ATP7B (3)

IFNg (1)

gB (2)

RNA-directed RNA polymerase L/ProteinL (1)

CD366/TIM-3 (2)

CD3E & Mesothelin & ALB (1)

CD184/CXCR4 (1)

RNase A (1)

F/Fusion glycoprotein F0 (10)

EGFR/ERBB1 (8)

Fusion Protein (1)

ADAMTS5 (2)

AKT1 (2)

NAP1L1 (1)

TACSTD2/TROP2 (1)

TK1 (1)

GSN/Gelsolin (4)

AaH II/Neurotoxin II (4)

CAT/Catalase (1)

Albumin/Alb (1)

CDKN2A/p16INK4a (1)

RdRp (1)

dsRed (1)

M1R (1)

Phl p 4 (1)

entC2/SEC2 (2)

PSA/KLK3 (1)

CD158a/KIR2DL1 (1)

GST 26 (1)

CD4 (1)

BLM (3)

IRSp53/BAIAP2 (1)

CD212/IL12RB1 (2)

CCL2/MCP-1 (1)

Betv1/Allergen Bet v 1-A (1)

CD114/CSF3R (1)

GFAP (2)

G9&A16 complex (2)

MLANA (1)

NOTCH1 (1)

DRD2 (6)

HIF1A (2)

PGF/PLGF (1)

gD/Envelope glycoprotein D (1)

CD309/VEGFR-2 (1)

mAb-1E7 (1)

NSP2 (1)

GPC3 (1)

HBEGF (1)

RNA polymerase complex (2)

CD28 (1)

CD56/NCAM1 (3)

SLC10A1 (3)

rev/ART/TRS (1)

S/Spike glycoprotein (2)

HTT (3)

Intact VWF (1)

SLC5A8 (6)

GPR68 (1)

CD331/FGFR1 (1)

stxB/SLT-1b/VT1 (2)

LRP6 (2)

CD66c/CEACAM6 (2)

AX/Amoxicillin (3)

CD156b/ADAM17 (1)

PTK7 (1)

ANGPT4 (1)

MAPT/Tau (4)

HTR2A (1)

ompA (2)

EPOR (2)

CD123/IL-3Rα (1)

CD262/TRAIL-R2/DR5 (3)

IFNG/IFN-gamma (1)

SERPINE1/PAI-1 (5)

GABRB3 (1)

CD339/JAG1 (1)

CTNNB1 (4)

LMO2 (2)

p-γ-H2AX (1)

EPEATag (2)

C4B (1)

CD45/PTPRC (8)

RBD (4)

TMPRSS2 (2)

CD156c/ADAM10 (1)

TNFa/TNF-alpha (4)

ADAM9 (1)

BoNT/B (5)

Vif/SOR protein (1)

Adiponectin/ADPN (1)

CD206/MRC1 (6)

CCT5 (1)

GP42/Glycoprotein 42 (2)

CHRM2 (2)

Nucleoporin Nup58/54/62 (1)

CD167b/DDR2 (1)

GAL-7/Galectin-7 (1)

Glycoprotein E2 (1)

higB-2 (7)

VIM/Vimentin (1)

TUFM (1)

SP140 (1)

KRAS (2)

GRM2 (1)

GABRA1 (1)

CGA/CG-alpha (1)

CD70 (2)

CAVIN1 (1)

ALFA tag (1)

SOST (1)

C3/Complement C3 (2)

AaH I/Neurotoxin I (1)

Protein P (2)

MMP13 (1)

MC4R (2)

Galectin-1 (1)

RHOB (2)

wlaB/pglK (1)

APOE (1)

A2AR/ADORA2A (1)

Thermostable GFP (1)

NadA/Neisseria adhesin A (2)

CD85a/LILRB3 (1)

CD340/ERBB2 (5)

ACTB/β-actin (1)

BACE2 (5)

PPIA (1)

GPHN/Gephyrin (1)

C3b/Complement C3b (1)

CD332/FGFR2 (1)

KCNA3 (1)

CD106/VCAM1 (2)

CD137/4-1BB (1)

PASM (1)

lgM (1)

FZD3 (2)

botA (4)

IL6 (2)

CD337/NCR3/NKp30 (2)

MAPK13 (1)

CD221/IGF1R (1)

CD279/PD-1 (1)

nup54.S/Nup54 (1)

5HT3/HTR3A (1)

CD273/PD-L2/PDCD1LG2 (1)

CD120a/TNFR1 (4)

PA/pagA/PA-83 (1)

CD124/IL4R (1)

SNCA/Alpha-synuclein (1)

babA2 (1)

H2-Ab1/MHCII (6)

ANGPT1 (1)

VRG4 (2)

CASP3/Caspase-3 (3)

CD31/PECAM1 (2)

CXCL12/SDF-1 (1)

Ricin (24)

ureB/Urease subunit beta (1)

Gn (1)

Capsid protein VP3 (1)

TNFα (2)

GAK (1)

CD20/MS4A1 (2)

ADAMTS13-cleaved VWF (1)

MMP12 (1)

IL12RB2 (1)

Fragilysin/btfP (2)

CFP/Properdin (2)

CFH (1)

Bet v 1/Allergen Bet v I-A (3)

CFTR (7)

ctxB/Cholera Toxin Subunit B (2)

SV2A (1)

Nav1.4 (2)

APP/Amyloid beta (2)

CD156a/ADAM8 (1)

PTH (1)

CD252/TNFSF4/OX40L (1)

E7/Protein E7 (4)

F (1)

CD18/ITGB2 (1)

ADRB2 (3)

A29L (16)

Envelope protein E (1)

CXCR7/ACKR3 (1)

Nucleoprotein (2)

ASIC1 (1)

G-quadruplex DNA (1)

FOS (1)

Mal f 1/Allergen Pit o 1 (16)

CDw210b/IL10RB (10)

CD3E (3)

CALCA/Calcitonin (1)

CD16a/FCGR3A (1)

FOLH1/PSMA (1)

RNA-directed RNA polymerase/NSP9 (1)

TP53/p53 (2)

LYZ (4)

Phl p 6 (2)

CD66e/CEA (4)

CD112/Nectin-2/PVRL2 (2)

2 (2)

CD7 (2)

CD197/CCR7 (1)

AFB1/Aflatoxin B1 (1)

Allergen Pis v 2/11S globulin (1)

Albumin/HSA & IFNAR1/IFNAR2 (1)

CXCL11/I-TAC (8)

ISG15 (4)

MDM4 (1)

LSP1 (1)

HCN4 (2)

gp120/Glycoprotein 120 (6)

CD64/FCGR1A (2)

STAT3 (1)

Complement C6 (1)

lexA/LexA repressor (1)

FURIN (2)

MTX/Methotrexate (2)

GST (1)

IGHM (1)

CASR (1)

Gag polyprotein (3)

CD32/FcgR2 (1)

CD284/TLR4 (1)

C4b/Complement C4b (2)

GPR183 (1)

PLAC1 (3)

CADM3/NECL-1/TSLL1 (5)

short-chain α-neurotoxin (1)

CD369/CLEC7A (1)

OLR1/LOX-1 (1)

TREM2 (4)

CD9 (2)

CD202b/TEK/TIE-2 (1)

CD182/CXCR2 (1)

Nav1.5 (2)

IL17F (1)

MLPH (1)

AZT/Aztreonam (2)

IgM (1)

BAX (2)

botA/BOTOX (20)

GBA (1)

PLAU (1)

DLL3 (1)

E7/ProteinE7 (1)

ASC/TMS1/PYCARD (2)

MSLN/Mesothelin (2)

stxB2/SLT-2b/VT2 (1)

IgE/IGHE (1)

Tenuazonic acid (3)

Spike glycoprotein (87)

Kappa Chain (5)

CD269/BCMA (1)

AGTR1 (2)

NP/Nucleoprotein (17)

CD230/PRNP (2)

xcpQ (1)

CD29/ITGB1 (1)

CD11a/ITGAL (1)

Lambda light chain (1)

CD71/TFRC (2)

MERS-CoV RBD (1)

CLDN18.2 (1)

4-D (2)

Toxin B/tcdB (2)

CD13/ANPEP/APN (11)

CD122/IL2RB (1)

GRM5 (2)

CD89/FCAR (1)

BCL2 (2)

CD72 (1)

OPRK1 (1)

VHH (10)

CX3CR1 (2)

MUC16/CA-125 (1)

CD86/B7-2 (2)

Alpha-cobratoxin (1)

ureC/glmM (1)

Toxin A/tcdA (2)

AURKA (1)

trxA/Thioredoxin (1)

ADRB1 (5)

EPHB6 (1)

EPHX2 (1)

VEGF/ANG-2 (1)

CD135/FLT3 (2)

H2AX (2)

CD132/IL2RG (1)

BACE1 (1)

CD209 (1)

COL1A1 (1)

ACKR1/CD234 (1)

C5/Complement C5 (1)

IL17RB (1)

FOLR1 (1)

CNR1/CB1 (4)

CD33 (1)

CEP164 (2)

PSIP1 (1)

CD40/TNFRSF5 (1)

OPRM1/μOR (1)

Enhanced GFP (1)

IL12B/IL-12 p40 (1)

ROR1/NTRKR1 (5)

porM (4)

VWF (4)

CCL3/MIP-1-alpha (2)

pglL (1)

ERBB3/HER3 (1)

LGR4 (3)

GFP (5)

CD268/TNFRSF13C/BAFFR (1)

HRH2 (1)

PAD4 (1)

InlB/Internalin B (2)

TG/Thyroglobulin (2)

Albumin/HSA (4)

SYNJ1 (2)

CD217/IL17RA (1)

CD254/RANKL/TNFSF11 (1)

APLNR/APJ (2)

Envelopeglycoprotein E2/gp55 (3)

CRMP1 (1)

babA (1)

CD370/CLEC9A (7)

VSIG4/CRIg (8)

PCSK9 (2)

CD14 (1)

DCX (2)

CD11b/ITGAM (6)

CD16/FcgR3 (1)

CD123/IL3RA (1)

VEGFA (2)

ARC (4)

E2 (1)

BIRC5 (1)

CD275/ICOSLG (1)

MET/HGFR (1)

CD223/LAG3 (3)

CD163 (1)

CD5/Ly-1 (4)

KRT19/CK19 (1)

MoonTag (1)

IgG1 Fc Fragment (1)

6*His Tag (1)

B2M/β2-MG (1)

SOD1 (1)

SYT1 (1)

GP/Glycoprotein (1)

mCherry (3)

RECQL5 (9)

ANGPTL4 (1)

Fab Fragment (1)

Microcystin-LR (2)

IL23A (1)

NCL (1)

TRPM4/LTRPC4 (1)

gD (2)

DKK1 (2)

CD49c/ITGA3 (1)

CD38/ADPRC 1 (5)

CDw210a/IL10RA (1)

GPR151 (1)

Capsid protein VP1 (1)

ANGPT2/ANG-2 (1)

KLB/Beta-klotho (2)

CD47/MER6 (6)

CD19 (2)

botA/BoNT (3)

DPP6 (1)

Capsid protein (6)

F0 (1)

entB/SEB (1)

CD126/IL6R (1)

Nup54 (1)

GPC3/Glypican3 (1)

CPB2/TAFI (5)

Trastuzumab (1)

CD366/HAVCR2/TIM-3 (2)

CD274/PD-L1 (12)

G protein (1)

SLC4A7 (1)

tetX/Tetanus toxin (1)

CD276/B7-H3 (1)

CCL5/RANTES (1)

TRPC3 (1)

Frataxin (2)

CD282/TLR2 (2)

PTCH1 (3)

CD3E & DLL3 & ALB (2)

CD16b/FCGR3B (3)

CD152/CTLA4 (8)
Species

0 selected

Human respiratory syncytial virus (HRSV) (3)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1)

Campylobacter jejuni subsp. (1)

Mouse (3)

Human (23)

Human immunodeficiency virus 1 (HIV-1) (1)

Poliovirus type 1 (PV1) (1)

Human cytomegalovirus (HCMV/HHV-5) (1)
Applications

0 selected

DB (5)

WB (121)

Research in vivo (20)

ELISA Functional assay (1)

Blocking (16)

Functional assay (2)

Inhibition (4)

IHC (18)

Neutralization (45)

IP (38)

FuncS (13)

EMSA (1)

in vivo neutralization (1)

BLI (1)

FCM (218)

Isotype Control (10)

BIF (7)

RIA (16)

Cyro-EM (1)

IF (83)

Bioactivity: FACS (20)

X-ray Crystallography (1)

Agonist (1)

ELISA (946)

SPR (114)

Functional assay (20)
Reactivity

0 selected

Hendra virus (HeV) (1)

Crimean-Congo hemorrhagic fever virus (CCHFV) (1)

Phleum pratense (Common timothy) (3)

Schistosoma japonicum (Blood fluke) (2)

Bovine (1)

Vaccinia virus (VACV) (4)

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1) (5)

Chikungunya virus (CHIKV) (1)

Influenza A virus (H3N2) (1)

Severe acute respiratory syndrome coronavirus (SARS-CoV) (2)

Rat (3)

Parainfluenza virus 5 (PIV5) (1)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (94)

Campylobacter jejuni (1)

General (24)

Enterobacteria phage H19B (Bacteriophage H19B) (2)

Alpaca (1)

Mengla virus (MLAV) (1)

Epstein-Barr virus (HHV-4) (Human herpesvirus 4) (2)

Classical swine fever virus (CSFV) (2)

Androctonus australis (Sahara scorpion) (5)

Neisseria meningitidis (3)

Porcine (7)

Xenopus laevis (African clawed frog) (3)

Human immunodeficiency virus type 1 (HIV-1) (12)

Bacillus anthracis (2)

Meleagris gallopavo (Wild turkey) (1)

Candida albicans (2)

Ricinus communis (Castor bean) (24)

Helicobacter pylori (4)

Dabie bandavirus (Severe fever with thrombocytopenia virus) (SFTSV) (Huaiyangshan banyangvirus) (1)

Poliovirus type 1 (PV1) (2)

Canine (2)

Bacteroides fragilis (2)

Betula pendula (European white birch) (Betula verrucosa) (4)

Vibrio cholerae (9)

Human papillomavirus 16 (HPV16) (9)

Human parainfluenza 3 virus (HPIV-3) (1)

Monkeypox virus (MPXV) (17)

Zika virus (ZIKV) (1)

Junin mammarenavirus (JUNV) (Junn mammarenavirus) (1)

Malassezia furfur (Pityriasis versicolor infection agent) (Pityrosporum furfur) (16)

Porcine reproductive and respiratory syndrome virus (PRRSV) (2)

Pistacia vera (Pistachio) (1)

Rabbit (2)

Clostridium botulinum (32)

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (9)

Escherichia phage 933W (Bacteriophage 933W) (1)

Alternaria (3)

Influenza A virus (H1N1) (4)

Human (545)

Vesicular stomatitis Indiana virus (VSIV) (6)

Pseudomonas aeruginosa (1)

Mouse (70)

Middle East respiratory syndrome-related coronavirus (MERS-CoV) (1)

Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2) (4)

Naja kaouthia (Monocled cobra) (1)

Clostridioides difficile (4)

Escherichia coli (6)

Porphyromonas gingivalis (4)

Bundibugyo virus (BDBV) (1)

Listeria monocytogenes (2)

Bovine viral diarrhea virus (BVDV) (Mucosal disease virus) (3)

Lake Victoria marburgvirus (MARV) (Marburg virus) (1)

Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) (2)

Microcystis aeruginosa (2)

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) (5)

Influenza A virus (1)

Reston ebolavirus (REBOV) (Reston Ebola virus) (1)

Norwalk virus (NoV) (6)

Staphylococcus aureus (3)

Human metapneumovirus (HMPV) (2)

Clostridium tetani (1)

Human respiratory syncytial virus A (HRSV-A) (9)

Nipah virus (NiV) (2)

Saccharomyces cerevisiae (Baker's yeast) (1)

Oropouche virus (OROV) (1)

Hepatitis C Virus (HCV) (1)

Tai Forest ebolavirus (TAFV) (Cote d'Ivoire Ebola virus) (1)

Bacillus cereus (1)

Sudan ebolavirus (SEBOV) (Sudan Ebola virus) (3)

Chicken (7)
Host species

0 selected

Mouse (123)

Human (135)

Alpaca (748)

Rat (5)
Clonality

0 selected

Monoclonal (1020)
Conjugate

0 selected

PE (22)

Unconjugated (934)

FITC (22)

APC (21)

PerCP (21)