Anti-Human CD151 Recombinant Antibody (TS151) (HW567013)

Name: Anti-Human CD151 Recombinant Antibody (TS151)
Brand: abinScience
SKU: HW567013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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SDS

Обзор

Каталожный номер

HW567013

Описание

Anti-Human CD151 Recombinant Antibody (TS151) (HW567013) is a human monoclonal antibody detecting CD151 in ELISA, FCM. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, FCM

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

TS151

Цель

CD151, CD151 antigen, GP27, Membrane glycoprotein SFA-1, PETA-3, Platelet-endothelial tetraspan antigen 3, TSPAN24, Tetraspanin-24, Tspan-24

Уровень эндотоксинов

< 10 EU/mg

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P48509

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

CD151 antigen is a ~28 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays a role in various cellular and molecular mechanism through its association with both integrin and non-integrin proteins. These interactions facilitate critical cellular functions, including cell-to-cell communication, wound healing, platelet aggregation, trafficking, cell motility, and angiogenesis. Via interaction with JAM-A/F11R and integrin ITGA3:ITGB1, promotes the recruitment of signaling molecules such as RAC1, CDC42 and RhoGTPases to facilitate the polarization of epithelial cells and the reorganization of the actin cytoskeleton, which are critical steps in cell migration process. Regulates the glycosylation pattern of ITGA3:ITGB1 thereby modulating its activity.

1. Zheng, ZZ. et al. (2007) The international journal of biochemistry & cell biology 39, 340-8. PMID: 17045834

2. Rocha-Perugini, V. et al. (2014) European journal of immunology 44, 1967-75. PMID: 24723389

3. Te Molder, L. et al. (2019) Journal of cell science 132. PMID: 31488507

4. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693

5. Thölmann, S. et al. (2022) Cellular and molecular life sciences : CMLS 79, 88. PMID: 35067832

6. Baldwin, G. et al. (2008) The Journal of biological chemistry 283, 35445-54. PMID: 18852263

7. Karamatic Crew, V. et al. (2004) Blood 104, 2217-23. PMID: 15265795

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human CD151 Recombinant Antibody (TS151).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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