

| Каталожный номер | HX902026 |
|---|---|
| Описание |
Anti-Human Tie-2 Reference Antibody (Dovarafusp Alfa, RUO) (HX902026) is a human monoclonal antibody detecting Tie-2.
|
| Реактивность видов | Human |
| Применения | ELISA, FCM, Functional assay |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa-VEGFR-1 |
| Цель | Angiopoietin-1 receptor, CD202b, EC:2.7.10.1, Endothelial tyrosine kinase, TEK, TIE2, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, VMCM, VMCM1, hTIE2, p140 TEK |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q02763 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| Альтернативные названия | CAS: 3082355-89-0 |
| Фон | Angiopoietin-1 receptor (CD202b/TEK) is a ~125 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. |
| Примечание | For research use only. |




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