Anti-Human CD202b/TEK/TIE-2 Reference Antibody (UBX2050, RUO) (HX902016)

Name: Anti-Human CD202b/TEK/TIE-2 Reference Antibody (UBX2050, RUO)
Brand: abinScience
SKU: HX902016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HX902016
Description	Anti-Human CD202b/TEK/TIE-2 (UBX2050) (HX902016) is a research-grade recombinant antibody targeting CD202. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	UBX2050
Expression system	Mammalian cells
Clonality	Monoclonal
Target	VMCM, TIE2, Tunica interna endothelial cell kinase, CD202b, Tyrosine-protein kinase receptor TIE-2, TEK, Angiopoietin-1 receptor, VMCM1, Endothelial tyrosine kinase, Tyrosine-protein kinase receptor TEK, p140 TEK, Tyrosine kinase with Ig and EGF homology domains-2, hTIE2
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q02763
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	UBX2050
Background	Angiopoietin-1 receptor (CD202b/TEK) is a ~125 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CD202b/TEK/TIE-2 (UBX2050)

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Anti-Human CD202b/TEK/TIE-2 Reference Antibody (UBX2050, RUO).pdf

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Anti-Human CD202b/TEK/TIE-2 Reference Antibody (UBX2050, RUO) (HX902016)

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