

| Каталожный номер | HW431046 |
|---|---|
| Описание |
Anti-Human CD79B Reference Antibody (Rebatatug, RUO) (HW431046) is a human monoclonal antibody detecting CD79B.
|
| Реактивность видов | Human |
| Применения | ELISA, FACS, Functional assay |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| Цель | B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, CD79B, CD79b, IGB, Ig-beta, Immunoglobulin-associated B29 protein |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P40259 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| Альтернативные названия | CAS: 3063160-97-1 |
| Фон | B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~26 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy). |
| Примечание | For research use only. |




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