InVivo Plus Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) (HC359019)

Name: InVivo Plus Anti-Human/Mouse/Rat CD47 Antibody (MIAP410)
Brand: abinScience
SKU: HC359019
Price: 128 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

1mg
5mg
25mg
50mg
100mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HC359019

Описание

InVivo Plus Anti-Human/Mouse/Rat CD47 Antibody(MIAP410) (HC359019) is a mouse monoclonal antibody detecting CD47 in ELISA, FCM, Functional assay, Research in vivo. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, FCM, Functional assay, Research in vivo

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1 kappa

ID клона

MIAP410

Цель

Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6

Уровень эндотоксинов

< 1 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Связанные продукты

pH 7.4 Dilution Buffer

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q08722, Q08722, P97829

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Доставка

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Leukocyte surface antigen CD47 (MER6) is a ~35 kDa protein. Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure. CD47 is the therapeutic target of magrolimab (clinical).

1. Latour, S. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 2547-54. PMID: 11509594

2. Piccio, L. et al. (2005) Blood 105, 2421-7. PMID: 15383453

3. Isenberg, JS. et al. (2009) The Journal of biological chemistry 284, 1116-25. PMID: 19004835

4. Lindberg, FP. et al. (1993) The Journal of cell biology 123, 485-96. PMID: 7691831

5. Gao, AG. et al. (1996) The Journal of biological chemistry 271, 21-4. PMID: 8550562

6. Rogers, NM. et al. (2017) Cardiovascular research 113, 15-29. PMID: 27742621

7. Ghimire, K. et al. (2020) Cells 9. PMID: 32679764

Примечание

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

Изображения

Ссылки

Даташит

InVivo Plus Anti-Human/Mouse/Rat CD47 Antibody (MIAP410).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

InVivo Plus Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) (HC359019)

Обзор

Изображения

Ссылки

Даташит

SDS