Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody (MIAP410) (HC359033)

Name: Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody (MIAP410)
Brand: abinScience
SKU: HC359033
Price: 191 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): $

Spec:

50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC359033

Species reactivity

Human, Mouse, Rat

Applications

ELISA, FACS, Functional assay, Research in vivo

Host species

Mouse

Isotype

IgG1, kappa

Clone ID

MIAP410

Clonality

Monoclonal

Target

Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6

Endotoxin level

<1 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q08722, Q61735, P97829

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Leukocyte surface antigen CD47 is a ~35 kDa protein. Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure.

1. Latour, S. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 2547-54. PMID: 11509594

2. Piccio, L. et al. (2005) Blood 105, 2421-7. PMID: 15383453

3. Isenberg, JS. et al. (2009) The Journal of biological chemistry 284, 1116-25. PMID: 19004835

4. Lindberg, FP. et al. (1993) The Journal of cell biology 123, 485-96. PMID: 7691831

5. Gao, AG. et al. (1996) The Journal of biological chemistry 271, 21-4. PMID: 8550562

6. Rogers, NM. et al. (2017) Cardiovascular research 113, 15-29. PMID: 27742621

7. Ghimire, K. et al. (2020) Cells 9. PMID: 32679764

Note

For research use only

Images

References

Datasheet

Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody (MIAP410).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody (MIAP410) (HC359033)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us