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| 카탈로그 번호 | HY195207 |
|---|---|
| 설명 |
Anti-Human CD45RO Antibody (UCHL1) [UCHL1] (HY195207) is a mouse monoclonal antibody detecting CD45 in FCM. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | FCM |
| 숙주 종 | Mouse |
| 이소타입 | IgG2a, kappa |
| 클론 ID | UCHL1 |
| 클론성 | Monoclonal |
| 타겟 | T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P08575 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951 |
| 참고사항 | For research use only. |
SEC-HPLC detection for Anti-Human CD45RO Antibody (UCHL1).
Detects CD45RO in indirect ELISAs.
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
