Anti-Human ROBO1 Recombinant Antibody (B5209B), FITC (HP485117)

Name: Anti-Human ROBO1 Recombinant Antibody (B5209B), FITC
Brand: abinScience
SKU: HP485117
Price: 223 USD
Availability: InStock

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Каталожный номер	HP485117
Описание	Anti-Human ROBO1 Recombinant Antibody (B5209B), FITC (HP485117) is a human monoclonal antibody detecting ROBO1 in FCM. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●FITC Conjugated — Ready for direct detection without secondary antibody.
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	B5209B
Конъюгация	FITC
Цель	ROBO1, Roundabout homolog 1, H-Robo-1
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q9Y6N7
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Roundabout homolog 1 (ROBO1) is a ~180 kDa protein. Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA. May be required for lung development. 1. Brose, K. et al. (1999) Cell 96, 795-806. PMID: 10102268 2. Leyva-Díaz, E. et al. (2014) Current biology : CB 24, 494-508. PMID: 24560577 3. Kong, R. et al. (2015) The Journal of clinical investigation 125, 4407-20. PMID: 26529257
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human ROBO1 Recombinant Antibody (B5209B), FITC.pdf

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Anti-Human ROBO1 Recombinant Antibody (B5209B), FITC (HP485117)

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