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Anti-Human CD334/FGFR4 Antibody (U3-17846J6Ye), FITC (HB856117)

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개요

카탈로그 번호	HB856117
설명	Anti-Human CD334/FGFR4 Antibody (U3-17846J6Ye), FITC [U3-17846J6Ye] (HB856117) is a mouse monoclonal antibody detecting FGFR4 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
이소타입	IgG1, kappa
클론 ID	U3-17846J6Ye
접합	FITC
클론성	Monoclonal
타겟	FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334
내독소 수준	Please contact with the lab for this information.
등록번호	P22455
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD334/FGFR4 Antibody (U3-17846J6Ye), FITC.pdf

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Anti-Human CD334/FGFR4 Antibody (U3-17846J6Ye), FITC