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| 카탈로그 번호 | MF998147 |
|---|---|
| 설명 |
Anti-Mouse CD4 Antibody (GK1.5), PerCP [GK1.5] (MF998147) is a rat monoclonal antibody detecting CD4 in FCM. Suitable for Mouse.
Highlights
|
| 종 반응성 | Mouse |
| 응용 분야 | FCM |
| 숙주 종 | Rat |
| 이소타입 | IgG2b |
| 클론 ID | GK1.5 |
| 접합 | PerCP |
| 클론성 | Monoclonal |
| 타겟 | T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4 |
| 내독소 수준 | Please contact with the lab for this information. |
| 등록번호 | P06332 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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