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Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP (HY596147)

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개요
카탈로그 번호HY596147
설명
Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP [SAA0019] (HY596147) is a rabbit monoclonal antibody detecting ITGA4 in ELISA, FCM. Suitable for Human.
Highlights
  • Rabbit Monoclonal — High specificity, affinity, and excellent lot-to-lot consistency.
  • Flow Cytometry — Validated for flow cytometry applications.
  • Fluorescent Label — Direct conjugate for streamlined workflows.
종 반응성Human
응용 분야ELISA, FCM
숙주 종Rabbit
이소타입IgG, kappa
클론 IDSAA0019
접합PerCP
클론성 Monoclonal
타겟 ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4
내독소 수준 Please contact with the lab for this information.
등록번호 P13612
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Store at 4°C for 12 months. Protect from light. Do not freeze.
배경

Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1.

1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415
2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536
3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877
4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
참고사항 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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