홈 > 제품 > 항체 > 플로우 사이토메트리 항체

Anti-Mouse CD47/MER6 Antibody (A4), PerCP (MC359147)

데이터시트 제품 공유 정보 복사

가격(USD): $

사양:

50T
100T

수량:

문의하기

개요
이미지
참고 문헌
데이터시트

개요

카탈로그 번호	MC359147
설명	Anti-Mouse CD47/MER6 Antibody (A4), PerCP [A4] (MC359147) is a mouse monoclonal antibody detecting CD47 in FCM. Suitable for Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
종 반응성	Mouse
응용 분야	FCM
숙주 종	Mouse
이소타입	VHH, mFc
클론 ID	A4
접합	PerCP
클론성	Monoclonal
타겟	Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47
내독소 수준	Please contact with the lab for this information.
등록번호	Q61735
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Leukocyte surface antigen CD47 (MER6) is a ~33 kDa protein. Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure. CD47 is the therapeutic target of magrolimab (clinical). 1. Bauer, EM. et al. (2010) Cardiovascular research 88, 471-81. PMID: 20610415 2. Kaur, S. et al. (2013) Scientific reports 3, 1673. PMID: 23591719 3. Rogers, NM. et al. (2017) Cardiovascular research 113, 15-29. PMID: 27742621 4. Manna, PP. et al. (2005) The Journal of biological chemistry 280, 29637-44. PMID: 15917238 5. Ghimire, K. et al. (2020) Cells 9. PMID: 32679764 6. Isenberg, JS. et al. (2008) Annals of surgery 247, 180-90. PMID: 18156939 7. Oldenborg, PA. et al. (2000) Science (New York, N.Y.) 288, 2051-4. PMID: 10856220
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

참고 문헌

데이터시트

Anti-Mouse CD47/MER6 Antibody (A4), PerCP.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

추천

문의하기 맞춤형 견적, 대량 주문 및 기타 문의 사항은

메일: support@abinScience.com

배급사 목록

Anti-Mouse CD47/MER6 Antibody (A4), PerCP