Human ErbB2/Her2 Antibody Pair Set (HY286908)

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Обзор
Изображения
Ссылки
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SDS
Protocol

Обзор

Каталожный номер	HY286908
Описание	Human ErbB2/Her2 Antibody Pair Set (HY286908) is a capture: human, detection: human antibody detecting ErbB2/Her2 in ELISA. Suitable for Human. Highlights ●Detection: Biotin Conjugated — Ready for direct detection without secondary antibody.
Чувствительность	14.9 pg/mL
Диапазон	78.1 - 5,000 pg/mL
Реактивность видов	Human
Хозяинский вид	Capture: Human, Detection: Human
Иммуноген	ErbB2/Her2
Конъюгация	Detection: Biotin
Проверенные приложения	S-ELISA
Цель	CD340, EC:2.7.10.1, ERBB2, HER2, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NGL, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2
Специфичность	ErbB2/Her2
Номер доступа	P04626
Применения	ELISA
Форма	Liquid
Буфер хранения	Capture: 0.01M PBS pH 7.4; Detection: 0.01M PBS pH 7.4, 50% glycerol Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Тип анализа	Sandwich ELISA
Характеристики	Reagents are sufficient for at least 1 x 96 well plates using recommended protocol.
Фон	Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. CD340 is the therapeutic target of trastuzumab (Herceptin) and trastuzumab deruxtecan (Enhertu).
Примечание	For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Изображения

Standard Curve

Standard Curve of Human ErbB2/Her2 Antibody Pair Set

Ссылки

Даташит

Human ErbB2/Her2 Antibody Pair Set.pdf

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Protocol

Download Protocol PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа