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| 카탈로그 번호 | VK665030 |
|---|---|
| 설명 |
InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) [1G2] (VK665030) is a human monoclonal antibody detecting Envelope glycoprotein B in ELISA, Neutralization.
|
| 종 반응성 | Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5) |
| 응용 분야 | ELISA, Neutralization |
| 숙주 종 | Human |
| 이소타입 | IgG1, kappa |
| 클론 ID | 1G2 |
| 클론성 | Monoclonal |
| 타겟 | Envelope glycoprotein B, gB, gB, UL55 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P13201 |
| RRID | InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) (abinScience Cat# VK665030, RRID:AB_3729517) |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)
Detects recombinant HCMV/HHV5 Envelope glycoprotein B/gB (Catalog No: VK665011) in indirect ELISA
Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HCMV/HHV5 Envelope glycoprotein B/gB(Catalog No: VK665011)
Lane 2: negative control
Lane 3: negative control
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