Research Grade Zenocutuzumab (HY286096)

データシート製品共有情報コピー

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100ug
1mg

数量:

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概要
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参考文献
データシート

概要

カタログ番号	HY286096
説明	Zenocutuzumab (HY286096) is a research-grade recombinant antibody targeting CD340. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Humanized
アイソタイプ	IgG1-kappa
発現システム	Mammalian Cells
クローン性	Monoclonal
ターゲット	p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3
エンドトキシンレベル	Please contact the lab for this information.
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P04626 & P21860
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名	Bispecific, MCLA-128, PB4188, R040517, 1969309-56-5
背景	Zenocutuzumab (MCLA-128) is a bispecific humanized IgG1 antibody containing two different Fab arms, targeting extracellular domains of HER2 and HER3.
注意事項	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD340/ERBB2/HER2/NEU in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Zenocutuzumab
Flow CytoMetry

Flow-cytometry using anti-human ERBB3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ERBB3 monoclonal antibody (Catalog: HY286096) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD340/ERBB2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD340/ERBB2 (Catalog No: HY286011)

参考文献

データシート

Research Grade Zenocutuzumab.pdf

Formula

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Working Solution

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Research Grade Zenocutuzumab (HY286096)

概要

イメージ

参考文献

データシート

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